Octa plasma. 5 days ago · This center in Houston, TX loca...

Inactivation of non-enveloped viruses by pooling and

Apr 15, 2007 · Enhanced labelling of the cytosol, nucleus and nucleolus was also achieved by extraction of plasma membrane cholesterol with methyl-beta-cyclodextrin. The data argue for two, temperature-dependent, uptake mechanism for these peptides and for the existence of a threshold concentration for endocytic uptake that when exceeded promotes direct ...5 days ago · About Plasma. EXPLORE. Donating plasma is a safe and easy way to help others. It takes about an hour and can help save multiple lives.This card allows donors direct access to funds available in their Paysign® account. The LFB Plasma PrePaid VISA is not a credit but a VISA debit card, which is loaded each time a donor donates plasma at one of our …Multiple myeloma is a blood cancer that starts in the plasma cells in the bone marrow. Bone marrow is the soft, spongy tissue found inside most bones in children and in the front c...Headquartered in Lachen, Switzerland, Octapharma is one of the largest human protein manufacturers in the world, developing and producing human proteins from human plasma and human cell lines. We employ more than 11,000 people worldwide to support the treatment of patients in 118 countries with products across three therapeutic areas ...Plasma pooling1: Dilution of any initial viral load. Immune neutralization2: Antibodies neutralize viral particles. Chromatography: (Prion Reduction) NAT testing 1: Viral levels below thresholds. Log reduction factor of Octaplasma® (log10) [DOF] [5] Adapted from Octapharma data on file. HAV >8.15;Jan 22, 2019 · All donor payments are loaded onto an Octapharma Plasma prepaid card after each successful donation, which can be used anywhere Visa and MasterCard are accepted. ... When making a purchase with my Octa card and I use the "cash back" option, how much cash can I ask for? 39w.Standardized levels of neutralizing antibodies in the plasma pool minimize the risk of transmitting non-enveloped viruses (e.g., HAV, parvovirus B19, HEV). 6. Plasma pooling1: Dilution of any initial viral load. Immune neutralization2: Antibodies neutralize viral particles. NAT testing 1: Viral levels below thresholds. See how working at CSL Plasma vs. Octapharma Plasma compares on a variety of workplace factors. By comparing employers on employee ratings, salaries, reviews, pros/cons, job openings and more, you'll feel one step ahead of the rest. All salaries and reviews are posted by employees working at CSL Plasma vs. Octapharma Plasma.Feb 14, 2024 · Find the address, telephone & hours of the closest Octapharma Plasma donation center in Milwaukee, WI near you. West Milwaukee, WI 145 – Miller Park Way. Milwaukee, WI 446 – W Brown Deer Rd. Octapharma Plasma, Inc. is a U.S.-based company that collects plasma used to create life-saving medicines for patients around the world.Plasma pooling1: Dilution of any initial viral load. Immune neutralization2: Antibodies neutralize viral particles. Chromatography: (Prion Reduction) NAT testing 1: Viral levels below thresholds. Log reduction factor of Octaplasma® (log10) [DOF] [5] Adapted from Octapharma data on file. HAV >8.15;705 N Park St Kalamazoo, MI 49007. Phone: (269) 349-2124. Hours: Mon-Sun 7:00am – 7:00pm. Located in close proximity to Family Dollar, Park Street Market and McDonald’s. We offer free parking and Wi-Fi, and we have a friendly and knowledgeable staff who is always happy to help. Nov 28, 2023 · Terms and conditions By clicking the ‘I Agree’ button, I confirm that I have read and agree to the terms and conditions set forth in the above policies, which are a condition to my use of this app. I Agree Cancel CancelErie, PA 113 – Peach Street. Whitehall, PA 111 – MacArthur Towne Center. York, PA 143 – Loucks Road. Octapharma Plasma, Inc. is a U.S.-based company that collects plasma used to create life-saving medicines for patients around the world. We run more than 150 Plasma Donation Centers in the U.S and employ more than 3,500 people nationally. Finding Internships and Internship Alternatives During COVID-19. If you are a new graduate or student who feels like your summer internship plans are in limbo due to the COVID-19 outbreak, you are not alone. Usually, at this time, people would be searching for, applying to and confirming their summer internships across the country.4 days ago · This center in Columbus, OH is located at: 3467 Cleveland Ave Columbus OH 43224. Phone: (614) 261-7019. Hours: Mon-Sun 7:00am – 7:00pm. Located in the same plaza as Fifth Third Bank and Clown Cones and Confections while just down the street from Autozone on Cleveland Ave . We offer free parking and Wi-Fi, and we have a friendly and ...Step 3: Earn points and redeem your prizes. Donors can earn points through actions like donating plasma, referring their friends, reaching new status levels, and even celebrating birthdays with us. The more points, the more status levels you’ll reach! In the OctaApp, you’ll see your current status level, available points to redeem, and ways ... 5 days ago · Furthermore, we offer competitive compensation to both new donors and those who’ve donated before. This center in Aurora, CO is located at: 15453 E Hampden Ave Aurora, CO 80013. Phone: (720) 545-2497. Hours: Mon- Sun 7:00am – 7:00pm. Located in the same plaza as Big Lots, Dollar Tree and Wing Hut Aurora. We offer free parking and …Octapharma Canada Inc., 2021. Heger A, Römisch J, aet al. A biochemical comparison of a pharmaceutically licensed coagulation active plasma (Octaplas) with a universally …The production process. We collect plasma and transform it into lifesaving plasma-derived therapies. Each plasma-derived therapy we create is controlled, fractionated, purified, virus inactivated and inspected before being used to change and save the lives of millions of patients worldwide. Plasma-based therapies treat rare, genetic and chronic ...anti-D immunoglobulinThis center in Moline, IL is located at: 6015 Fort Ave Lynchburg, VA 24502. Phone: (434) 237-6861. Hours: Sun – Sat 7:00am – 6:00pm. Located in close proximity to the Fort Hill Bowling Center, Fort Hill Post Office and the Lynchburg Pawn Shop. We offer free parking and Wi-Fi, and we have a friendly and knowledgeable staff who is always ... 3 days ago · Our center in Houston, TX is located at: 10945 Farm to Market 1960 Rd W, Houston, TX 77070. Phone: (281) 640-3065. Hours: Monday-Sunday 7am-7pm. Just steps away from the Wendy’s off of Windfern Rd and the Walgreens who all sit within the Jones Square Shopping Mall. We offer free parking and Wi-Fi, and we have a friendly and …Octapharma New Donor Pay. Octapharma New Donor Pay ranges from $50 to $75 per donation, depending on the donor’s body weight and donation type. New donors can earn up to $400 a month, with additional rewards and bonuses throughout the year. Payments are made through the Octapharma Plasma prepaid card.923 customer reviews of Octapharma Plasma. One of the best Blood & Plasma Donation Centers businesses at 4760 S Kedzie Ave, Chicago, IL 60632 United States. Find reviews, ratings, directions, business hours, and book appointments online.3 days ago · Sacramento, CA 468 – Fruitridge Rd. Bakersfield, CA 826 – Oak St. Indio, CA 177 – Highway 111. Octapharma Plasma, Inc. is a U.S.-based company that collects plasma used to create life-saving medicines for patients around the world. We run more than 150 Plasma Donation Centers in the U.S and employ more than 3,500 people nationally.5 days ago · Furthermore, we offer competitive compensation to both new donors and those who’ve donated before. This center in Aurora, CO is located at: 15453 E Hampden Ave Aurora, CO 80013. Phone: (720) 545-2497. Hours: Mon- Sun 7:00am – 7:00pm. Located in the same plaza as Big Lots, Dollar Tree and Wing Hut Aurora. We offer free parking and …Octaplas® is human plasma for infusion of pharmaceutical grade with standardized quality and unique safety profiles due to their integrated pathogen safety concept that represents state-of-the-art security for patients. The standardized content in octaplas® is achieved by pooling between 630 and 1520 single plasma units from multiple donors. 1. 3 days ago · Step 1: Determine your # of donations for the last 35 days by filling in your information in the form. Step 2: Determine your level based on your number of donations. Step 3: Identify your weight class and find your payment. Charts to determine steps 2 and 3 are available at your local donation center.I'm planning on buying a new television but I'm not sure what kind to get. I understand the difference in features, but I don't know the benefits and downsides of ...Independence, KCMO 445 – S Noland Rd. Kansas City, KCKS 495 – State Ave. Missouri Plasma Centers. Octapharma Plasma, Inc. is a U.S.-based company that collects plasma used to create life-saving medicines for patients around the world. We run more than 150 Plasma Donation Centers in the U.S and employ more than 3,500 people nationally. 3 days ago · The technical storage or access is strictly necessary for the legitimate purpose of enabling the use of a specific service explicitly requested by the subscriber or user, or for the sole purpose of carrying out the transmission of a communication over an electronic communications network.3 days ago · The technical storage or access is strictly necessary for the legitimate purpose of enabling the use of a specific service explicitly requested by the subscriber or user, or for the sole purpose of carrying out the transmission of a communication over an electronic communications network.4 days ago · Additionally, we provide competitive compensation to new donors as well as returning ones. This center in Hudson, FL is located at: 12142 US-19 Hudson FL 34667. Phone: (727) 755-0230. Hours: Sun – Sat 7:00am – 7:00pm. Located in the same plaza as Save A Lot and across the street from Waffle House and CVS Pharmacy.Octapharma Plasma is a medical company that uses your plasma to create a number of life-saving medicines that treat patients with rare, chronic, and inherited diseases. These plasma-based medicines are used in emergency medicine or trauma, for bleeding disorders like hemophilia, and to treat patients whose bodies have trouble fighting ...Orlando, FL 480 – N Semoran Blvd. Orlando, FL 449 – Silver Star Rd. Florida Plasma Centers – 14 Plasma Centers. Octapharma Plasma, Inc. is a U.S.-based company that collects plasma used to create life-saving medicines for patients around the world. We run more than 150 Plasma Donation Centers in the U.S and employ more than 3,500 people ... Find the address, telephone, & hours of the closest Octapharma Plasma donation center in the Tampa Bay-St Petersburg Metropolitan Area near you. – Central Ave. – Patricia Ave. Hudson, FL 159 – US Hwy 19. Octapharma Plasma, Inc. is a U.S.-based company that collects plasma used to create life-saving medicines for patients around the world. This center in Tulsa, OK located at: 11523 E 31st St, Tulsa, OK 74146. Phone: (918) 894-6424. Hours: Mon-Fri 7:00am – 5:00pm, Sat – Sun 8:00am – 5:00pm. Located in close proximity to Tulsa Fire Station #27, CashSavers Groceries and Advanced Auto Parts. We offer free parking and Wi-Fi, and we have a friendly and knowledgeable staff who is ... Plasma pooling1: Dilution of any initial viral load. Immune neutralization2: Antibodies neutralize viral particles. Chromatography: (Prion Reduction) NAT testing 1: Viral levels below thresholds. Log reduction factor of Octaplasma® (log10) [DOF] [5] Adapted from Octapharma data on file. HAV >8.15;Feb 1, 2024 · The Octapharma Plasma App makes donating plasma, saving lives, and earning money just that much faster & easier. Download now!This card allows donors direct access to funds available in their Paysign® account. The LFB Plasma PrePaid VISA is not a credit but a VISA debit card, which is loaded each time a donor donates plasma at one of our …5 days ago · Furthermore, we offer competitive compensation to both new donors and those who’ve donated before. This center in Milwaukee, WI is located at: 1728 Miller Park Way West Milwaukee, WI 53214. Phone: (414) 999-3543. Hours: Mon- Sun 7:00am – 7:00pm. Located in the same plaza as the Aldi, Applebees and Speedway. We offer free parking …10 Jul 2019 ... At Octapharma Plasma's state-of-the-art laboratory, you'll find meaningful work that saves lives. Our lab employees are proud to work in a ...Search. Donate plasma today at a CSL Plasma center near you. You can make a difference and save lives by donating plasma. Learn more through cslplasma.com.Moreover, we ensure competitive compensation for both new and returning donors. This center in Oklahoma City, OK is located at: 2930 SW 59th St Oklahoma City, OK 73119. Phone: (405) 686-9226. Hours: Mon-Sun 7:00am – 7:00pm. Located in close proximity to the Subway, Family Dollar and AutoZone. We offer free parking and Wi-Fi, and we have a ... Octapharma develops and produces high-quality human proteins from human plasma and human cell lines. Products Learn more about our products to treat rare diseases and …Step 3: Earn points and redeem your prizes. Donors can earn points through actions like donating plasma, referring their friends, reaching new status levels, and even celebrating birthdays with us. The more points, the more status levels you’ll reach! In the OctaApp, you’ll see your current status level, available points to redeem, and ways ... Oct 25, 2023 · Your earning potential for selling plasma will depend on a variety of factors. You can expect $20 to $50 per donation. The specific amount will depend on the volume of plasma you are permitted to donate each time. The FDA sets guidelines for plasma donation. It is based on your body weight.Find the address, telephone, & hours of the closest Octapharma Plasma donation center in the Tampa Bay-St Petersburg Metropolitan Area near you. – Central Ave. – Patricia Ave. Hudson, FL 159 – US Hwy 19. Octapharma Plasma, Inc. is a U.S.-based company that collects plasma used to create life-saving medicines for patients around the world. 4 days ago · This center in Milwaukee, WI is located at: 8602 W Brown Deer Rd Milwaukee, WI 53224. Phone: (414) 586-0045. Hours: Mon-Fri 7:00am – 7:00pm. Located in close proximity to K&G Fashion Superstore, Chase Bank on Brown Deer Rd and Firestone. We offer free parking and Wi-Fi, and we have a friendly and knowledgeable staff who is …Mar 3, 2021 · STN: 125416 Proper Name: Pooled Plasma (Human), Solvent/Detergent Treated Tradename: Octaplas Manufacturer: Octapharma Pharmazeutika Produktionsges.m.b.H. Indication: Replacement of multiple ... We are the largest privately owned and independent plasma fractionator in the world. Our medicines are high-quality human proteins sourced from human plasma and human cell lines. About Octapharma. Diseases & …3 days ago · This center in Ypsilanti, MI is located at: 813 W Michigan Ave Ypsilanti, MI 48197. Phone: (734) 483-2084. Hours: Mon-Sun 7:00am – 7:00pm. Located in the same vicinity of Growing Hope Urban Farm, Michigan Avenue Animal Hospital and A Taste Of Soul By Biggie. We offer free parking and Wi-Fi, and we have a friendly and …Apr 7, 2023 · While she doesn't remember much from that day, she recalls what saved her life: a plasma transfusion. Read the Story. News & Stories. Check out our latest stories. 08/08/2023. Innovation and science. Driven by curiosity. 10/07/2023. Donor Stories. My son is a warrior! 04/07/2023. Corporate news.Your Pioneer plasma TV offers multiple HDMI inputs for connecting various high-definition video sources. Aside from video quality, using an HDMI input offers the additional advanta...3 days ago · This center in Aurora, IL is located at: 418 Hill Ave Aurora, IL 60505. Phone: (630) 375-0228. Hours: Mon-Sun 8:00am – 5:00pm. Located within a mile of Fox Valley Cycles, Life Storage Aurora and just across the street from Dollar General. We offer free parking and Wi-Fi, and we have a friendly and knowledgeable staff who is always happy …Getting a good night’s sleep is essential for overall health and wellbeing. But sometimes, no matter how comfortable your mattress is, it can still be difficult to get the rest you...Additionally, we offer competitive compensation for both new and returning. This center in Bakersfield, CA is located at: 118 Oak St Bakersfield, CA 93304. Phone: (661) 578-5768. Hours: Mon- Sat 7:00am – 7:00pm. Located in close proximity to KFC, Dollar General and Mobil on Oak Street. We offer free parking and Wi-Fi, and we have a friendly ... This card allows donors direct access to funds available in their Paysign® account. The LFB Plasma PrePaid VISA is not a credit but a VISA debit card, which is loaded each time a donor donates plasma at one of our …This center in Raleigh, NC is located at: 3901 Capital Blvd. Suite 125 Raleigh, NC 27604. Phone: (919) 746-9831. Hours: Mon 9:00am-5:00pm; Tues– Sun 7:00am – 7:00pm. Located within steps of El Pollo Rico, Walgreens and the Jiffy Lube on Capital BLVD. We offer free parking and Wi-Fi, and we have a friendly and knowledgeable staff who is ... 9 Dec 2020 ... On September 27, 2019 plaintiffs brought this lawsuit against Octapharma, CSL, ImmunoTek, and BioLife, alleging in their third amended complaint ...Quality & safety. Octapharma has an international reputation for the safety and quality of its products. We strive for the highest quality throughout the entire production process. Learn all our quality and safety measures. Learn more about our products to treat rare diseases and other coagulopathies and bleeding disorders.2 days ago · This center in Florence, AL is located at: 887 Florence Blvd Florence, AL 35630. Phone: (256) 767-0493. Hours: Mon-Fri 7:00am – 7:00pm. Located in close proximity of Jack’s, the Shell on Florence Blvd and down the street from Midgard SelfStorage . We offer free parking and Wi-Fi, and we have a friendly and knowledgeable staff who is …5 days ago · Furthermore, we offer competitive compensation to both new donors and those who’ve donated before. This center in Aurora, CO is located at: 15453 E Hampden Ave Aurora, CO 80013. Phone: (720) 545-2497. Hours: Mon- Sun 7:00am – 7:00pm. Located in the same plaza as Big Lots, Dollar Tree and Wing Hut Aurora. We offer free parking and …The production process. We collect plasma and manufacture it into lifesaving plasma-derived therapies. Each plasma-derived therapy we create is controlled, fractionated, purified, virus inactivated and inspected before being used to change and save the lives of millions of patients worldwide. Plasma-based therapies treat rare, genetic and ... The production process. We collect plasma and transform it into lifesaving plasma-derived therapies. Each plasma-derived therapy we create is controlled, fractionated, purified, virus inactivated and inspected before being used to change and save the lives of millions of patients worldwide. Plasma-based therapies treat rare, genetic and chronic ...With a multitude of plasma donation centers spread across the country, you’ll find a convenient option. Plus, we offer competitive compensation to both newcomers and those who’ve donated before. This center in Columbia, SC is located at: 50 Newmarket Square Newport News, VA 23605. Phone: (803) 454-9053. Hours: Mon – Sun 6:30am – 6:30pm. 4 days ago · This center in Milwaukee, WI is located at: 8602 W Brown Deer Rd Milwaukee, WI 53224. Phone: (414) 586-0045. Hours: Mon-Fri 7:00am – 7:00pm. Located in close proximity to K&G Fashion Superstore, Chase Bank on Brown Deer Rd and Firestone. We offer free parking and Wi-Fi, and we have a friendly and knowledgeable staff who is …Apr 7, 2023 · The new OPI brand has a very different look and feel. It uses lifestyle imagery that is designed to resonate with donors. “We bring relationships, emotions and impact to the forefront, and we have introduced distinctive graphical elements and designs that will unmistakably identify OPI,” says Bre Byrne, Director of Brand Strategy and Donor ...923 customer reviews of Octapharma Plasma. One of the best Blood & Plasma Donation Centers businesses at 4760 S Kedzie Ave, Chicago, IL 60632 United States. Find reviews, ratings, directions, business hours, and book appointments online.Find out your: Debit Card Information. Last 3 Donations Dates. Number of Donations in 35 Day Cycle. We look forward to providing you access to additional information in the coming weeks! Receive bonuses when friends and family donate! Start Now: Download OctaApp today! What is plasma used for? How long does it take to donate plasma? Where can I learn more about Octapharma Plasma? Eligibility Can I donate? ¿Puedo donar si solo hablo español? Can you donate plasma if you have a tattoo or piercing? Does my blood type matter? First Visit What should I bring with me? What will my first visit be like? 3363 Buford Hwy NE Atlanta, GA 30329. Phone: (404) 471-9921. Hours: Mon- Sun 7:00am – 7:00pm. Located in the same plaza as Dollar General, Goodwill and NCG Cinemas. We offer free parking and Wi-Fi, and we have a friendly and knowledgeable staff who is always happy to help. We also offer competitive compensation for new and returning donors. Octapharma | 47,117 followers on LinkedIn. Our passion drives us to provide new health solutions advancing human life | Headquartered in Lachen, Switzerland, Octapharma is one of the largest human protein manufacturers in the world, developing and producing human proteins from human plasma and human cell lines. Octapharma employs more than …Jan 24, 2024 · 了解Octapharma AB (奥克特珐玛Ab公司)公司的药物管线,治疗领域,技术平台,以及它的1项临床试和12篇文献,疾病领域:血液及淋巴系统疾病,技术平台:重组蛋 …Plasma, a component of human blood, is used to treat people suffering from medical emergencies. Injuries sustained from accidents, such as burns, trauma and shock, are treated with...Octaplasma® Product Monograph – English/French. A: Octaplasma® is contraindicated in patients with IgA deficiency with documented antibodies against IgA as it may cause …3363 Buford Hwy NE Atlanta, GA 30329. Phone: (404) 471-9921. Hours: Mon- Sun 7:00am – 7:00pm. Located in the same plaza as Dollar General, Goodwill and NCG Cinemas. We offer free parking and Wi-Fi, and we have a friendly and knowledgeable staff who is always happy to help. We also offer competitive compensation for new and returning donors. View the profiles of people named Octa Plasma. Join Facebook to connect with Octa Plasma and others you may know. Facebook gives people the power to...Octapharma Plasma collects, tests, and supplies plasma used in making life-saving medicines for patients in your community and around the world. Features: Location. · Find plasma donation centers near you. Next Donation. · View your next eligible date to donate plasma. OctaPass. · Complete the health questionnaire via the app and skip the kiosk!Top 5 Octapharma Plasma Promotions. The top 5 Octapharma Plasma Promotions are: 1. New Donor Bonus. First time plasma donors are eligible for a New Donor Bonus. The bonus amount can vary by location, but it could be a few hundred dollars during the first month. To qualify, new donors can earn $50 for each of their first five plasma donations.Headquartered in Lachen, Switzerland, Octapharma is one of the largest human protein manufacturers in the world, developing and producing human proteins from human plasma and human cell lines. We employ more than 11,000 people worldwide to support the treatment of patients in 118 countries with products across three therapeutic areas ...Moreover, we ensure competitive compensation for both new and returning donors. This center in Oklahoma City, OK is located at: 2930 SW 59th St Oklahoma City, OK 73119. Phone: (405) 686-9226. Hours: Mon-Sun 7:00am – 7:00pm. Located in close proximity to the Subway, Family Dollar and AutoZone. We offer free parking and Wi-Fi, and we have a ... Getting a good night’s sleep is essential for overall health and wellbeing. But sometimes, no matter how comfortable your mattress is, it can still be difficult to get the rest you...Plasma cutting is a widely used industrial process that involves cutting through various metals using a plasma torch. The process can be challenging, especially when dealing with t...Fresh frozen plasma is administered as an intravenous infusion at a maximum rate of 1 milliliter per kilogram per minute. The volume of each unit of fresh frozen plasma is between ...4 days ago · Our center in Chicago, IL is located at: 1947 W 95th St Chicago, IL 60643. Phone: (773) 941-7555. Hours: Mon – Sun 7:00am – 7:00pm. Located in the same plaza as Family Dollar, DTLR and Boost Mobile. We offer free parking and Wi-Fi, and we have a friendly and knowledgeable staff who is always happy to help. We also offer competitive ...3363 Buford Hwy NE Atlanta, GA 30329. Phone: (404) 471-9921. Hours: Mon- Sun 7:00am – 7:00pm. Located in the same plaza as Dollar General, Goodwill and NCG Cinemas. We offer free parking and Wi-Fi, and we have a friendly and knowledgeable staff who is always happy to help. We also offer competitive compensation for new and returning donors. Jan 4, 2024 · Octapharma Plasma, along with BioLife and CSL Plasma, is one of the highest paying plasma donation centers in the country. But their pay structure can be confusing and that’s where an Octapharma Plasma Pay Chart can come in handy. Octapharma Plasma has more than 150 locations across 35 U.S. states. To locate a donation center near you, …We are the largest privately owned and independent plasma fractionator in the world. Our medicines are high-quality human proteins sourced from human plasma and human cell lines. About Octapharma. Diseases & …. Find out your: Debit Card Information. Last 3 Donations DateIn the USA, Octapharma Plasma, Inc. collects, tests an Octaplas® is human plasma for infusion of pharmaceutical grade with standardized quality and unique safety profiles due to their integrated pathogen safety concept that represents state-of-the-art security for patients. The standardized content in octaplas® is achieved by pooling between 630 and 1520 single plasma units from multiple donors. 1. octaplasLG® is human plasma for infusion of pharmaceutical You now have access to OctaPass with the new OctaApp! Use your existing OctaPass login details to sign in to the app. A faster, easier way to complete the health questionnaire every time you donate. NOTE: If you do not have the OctaApp – Use the link below to access OctaPass. Octapharma has grown into a truly global...

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